Posts for tag: inflammation
Patients with chronic plaque psoriasis get better when they lose weight via a low-calorie diet:
March 10, 2014
Diet improves tx response in obese with plaque psoriasis
Patients with chronic stable plaque-type psoriasis who lose weight by adopting lifestyle changes appear to respond better to psoriasis treatment, according to study findings from Thailand.
In addition, quality of life, triglyceride and LDL cholesterol levels also improved with the lifestyle modifications, including a low-calorie diet. Previous studies have shown the relative risk of psoriasis is directly related to body mass index (BMI), and positive correlation exists between psoriasis severity and BMI.
Dermatologist From Upper East Side NY Explains Psoriasis, Metabolic Syndrome in Psoriasis , Psoriasis Severity Predicts Other Diseases, Psoriasis and Crohn's Disease ,The Size of Your Tonsils is Related to Psoriasis Severity, Psoriasis
Are you freaked out by the thought of the biliions of bacteria on you skin, imouth and gut? Please watch this entertaining video to get a better understanding of the critical importance of keeping a healthy balance of native bacteria in and on our bodies.
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Patients with psoriasis are almost nine times more likely to have enlarged tonsils, compared with patients without psoriasis, according to the results of a small study by Dr. Marianna Shvartsbeyn and her coinvestigators, reported at the American Academy of Dermatology’s Summer Academy Meeting. The study was supported by grants from the National Cancer Institute, the National Institute for Allergy and Infectious Diseases, and the National Institute of Dental and Craniofacial Research.
Patients with psoriasis were found to have had an odds ratio of 8.77 for having enlarged tonsils (grade 2 or greater), compared with healthy controls. Tonsillar size also was significantly larger in patients with psoriasis (mean tonsil grade, 1.78), than in control patients (mean tonsil grade, 0.86); the severity of psoriasis was positively associated with tonsil size, Dr. Shvartsbeyn and her colleagues reported.
Limited clinical data have suggested that there is an association between enlarged tonsils and inflammatory skin disease. Small studies have shown that among patients with psoriasis, the skin lesions disappeared or improved after tonsillectomy."Our hypothesis is that in chronic tonsillar hypertrophy, bacterial species that reside in the tonsils are released into the circulation and cause stimulation of T cells. As a result of this constant chronic stimulation, an autoreactive clone may be formed. The auto-clone may produce an antibody attacking the skin and drive inflammatory response. In some individuals, this exaggerated immune response may manifest as psoriasis," the investigators wrote.
And although there is empirical evidence "that tonsillectomy improved skin lesions in patients with psoriasis..., further studies are needed." Dr. Shvartsbeyn noted in an interview.
For more information, go to: http://www.skinandallergynews.com/index.php?id=1059&type=98&tx_ttnews[tt_news]=136913&cHash=da03e20e36
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